Publications

2023
Andrey Popugailo, Rotfogel, Ziv , Levy, Michal , Turgeman, Orli , Hillman, Dalia , Levy, Revital , Arad, Gila , Shpilka, Tomer , and Kaempfer, Raymond . 2023. “The Homodimer Interfaces Of Costimulatory Receptors B7 And Cd28 Control Their Engagement And Pro-Inflammatory Signaling”. Journal Of Biomedical Science, 30, Pp. 49.
2022
Tomer Shpilka, Naresh, Nandhitha Uma, Du, Yunguang , Watts, Jennifer L, and Haynes, Cole M. 2022. “Atfs-1 Regulates Peroxisome Assembly Genes And Protects Both Mitochondria And Peroxisomes During Peroxin Perturbations”. Biorxiv, Pp. 2022–09.
Qiyuan Yang, Liu, Pengpeng , Anderson, Nadine S, Shpilka, Tomer , Du, Yunguang , Naresh, Nandhitha Uma, Li, Rui , Zhu, Lihua Julie, Luk, Kevin , Lavelle, Josh , and others, . 2022. “Lonp-1 And Atfs-1 Sustain Deleterious Heteroplasmy By Promoting Mtdna Replication In Dysfunctional Mitochondria”. Nature Cell Biology, 24, Pp. 181–193.
Nandhitha Uma Naresh, Kim, Sookyung , Shpilka, Tomer , Yang, Qiyuan , Du, Yunguang , and Haynes, Cole M. 2022. “Mitochondrial Genome Recovery By Atfs-1 Is Essential For Development After Starvation”. Cell Reports, 41.
2021
Tomer Shpilka, Du, Yunguang , Yang, Qiyuan , Melber, Andrew , Naresh, Nandhitha Uma, Lavelle, Joshua , Kim, Sookyung , Liu, Pengpeng , Weidberg, Hilla , Li, Rui , and others, . 2021. “Uprmt Scales Mitochondrial Network Expansion With Protein Synthesis Via Mitochondrial Import In Caenorhabditis Elegans”. Nature Communications, 12, Pp. 479.
2020
Zachary J Milstone, Saheera, Sherin , Bourke, Lauren M, Shpilka, Tomer , Haynes, Cole M, and Trivedi, Chinmay M. 2020. “Histone Deacetylases 1 And 2 Silence Cryptic Transcription To Promote Mitochondrial Function During Cardiogenesis”. Science Advances, 6, Pp. eaax5150.
2018
Tomer Shpilka and Haynes, Cole M. 2018. “The Mitochondrial Upr: Mechanisms, Physiological Functions And Implications In Ageing”. Nature Reviews Molecular Cell Biology, 19, Pp. 109–120.
2015
Tomer Shpilka, Welter, Evelyn , Borovsky, Noam , Amar, Nira , Shimron, Frida , Peleg, Yoav , and Elazar, Zvulun . 2015. “Fatty Acid Synthase Is Preferentially Degraded By Autophagy Upon Nitrogen Starvation In Yeast”. Proceedings Of The National Academy Of Sciences, 112, Pp. 1434–1439.
Tomer Shpilka, Welter, Evelyn , Borovsky, Noam , Amar, Nira , Mari, Muriel , Reggiori, Fulvio , and Elazar, Zvulun . 2015. “Lipid Droplets And Their Component Triglycerides And Steryl Esters Regulate Autophagosome Biogenesis”. The Embo Journal, 34, Pp. 2117–2131.
Tomer Shpilka and Elazar, Zvulun . 2015. “Lipid Droplets Regulate Autophagosome Biogenesis”. Autophagy, 11, Pp. 2130–2131.
2012
Tomer Shpilka and Elazar, Zvulun . 2012. “Essential Role For The Mammalian Atg8 Isoform Lc3C In Xenophagy”. Molecular Cell, 48, Pp. 325–326.
David C Rubinsztein, Shpilka, Tomer , and Elazar, Zvulun . 2012. “Mechanisms Of Autophagosome Biogenesis”. Current Biology, 22, Pp. R29–R34.
Tomer Shpilka, Mizushima, Noboru , and Elazar, Zvulun . 2012. “Ubiquitin-Like Proteins And Autophagy At A Glance”. Journal Of Cell Science, 125, Pp. 2343–2348.
2011
Tomer Shpilka, Weidberg, Hilla , Pietrokovski, Shmuel , and Elazar, Zvulun . 2011. “Atg8: An Autophagy-Related Ubiquitin-Like Protein Family”. Genome Biology, 12, Pp. 1–11.
Gila Arad, Levy, Revital , Nasie, Iris , Hillman, Dalia , Rotfogel, Ziv , Barash, Uri , Supper, Emmanuelle , Shpilka, Tomer , Minis, Adi , and Kaempfer, Raymond . 2011. “Binding Of Superantigen Toxins Into The Cd28 Homodimer Interface Is Essential For Induction Of Cytokine Genes That Mediate Lethal Shock”. Plos Biology, 9, Pp. e1001149.
Hilla Weidberg, Shpilka, Tomer , Shvets, Elena , Abada, Adi , Shimron, Frida , and Elazar, Zvulun . 2011. “Lc3 And Gate-16 N Termini Mediate Membrane Fusion Processes Required For Autophagosome Biogenesis”. Developmental Cell, 20, Pp. 444–454.
Tomer Shpilka and Elazar, Zvulun . 2011. “Shedding Light On Mammalian Microautophagy”. Developmental Cell, 20, Pp. 1–2.
2010
Hilla Weidberg, Shvets, Elena , Shpilka, Tomer , Shimron, Frida , Shinder, Vera , and Elazar, Zvulun . 2010. “Lc3 And Gate-16/Gabarap Subfamilies Are Both Essential Yet Act Differently In Autophagosome Biogenesis”. The Embo Journal, 29, Pp. 1792–1802.
Hilla Weidberg, Shpilka, Tomer , Shvets, Elena , and Elazar, Zvulun . 2010. “Mammalian Atg8S: One Is Simply Not Enough”. Autophagy, 6, Pp. 808–809.